Part Jurassic Park part Game of Thrones a company claims to have resurrected the Dire Wolf. Named Romulus, Remus and…Khaleesi; the young pups have modified modern gray wolf DNA with the physical traits of the dire wolf, a species extinct for 12,000 years. The company is a start up, Colossal Biosciences, run by Ben Lamm and George Church, and they are looking to other “charismatic megafauna” to bring back with eyes on the wooly mammoth. The New Yorker takes a deep dive into the project
From a statement on Business Wire:
The three litters of Colossal’s dire wolves include two adolescent males (Romulus and Remus) and one female puppy (Khaleesi). Colossal also birthed two litters of red wolves from three different genetic founder lines. These litters include one adolescent female red wolf (Hope) and three male red wolf puppies (Blaze, Cinder, and Ash).
“Preserving, expanding, and testing genetic diversity should be done well before important endangered animal species like the red wolf are lost. Another source of ecosystem variety stems from our new technologies to de-extinct lost genes, including deep ancient DNA sequencing, polyphyletic trait analyses, multiplex germline editing, and cloning. The dire wolf is an early example of this, including the largest number of precise genomic edits in a healthy vertebrate so far. A capability that is growing exponentially,” said Harvard geneticist and co-founder of Colossal, Dr. George Church.
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